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Ultraviolet Light Induces Apoptosis via Direct Activation of CD95 (Fas/APO-1) Independently of Its Ligand CD95L

Induction of apoptosis in keratinocytes by UV light is a critical event in photocarcinogenesis. Although p53 is of importance in this process, evidence exists that other pathways play a role as well. Therefore, we studied whether the apoptosis-related surface molecule CD95 (Fas/APO-1) is involved. T...

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Autori principali: Aragane, Yoshinori, Kulms, Dagmar, Metze, Dieter, Wilkes, Gabriele, Pöppelmann, Birgit, Luger, Thomas A., Schwarz, Thomas
Natura: Artigo
Lingua:Inglês
Pubblicazione: The Rockefeller University Press 1998
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC2132609/
https://ncbi.nlm.nih.gov/pubmed/9425165
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