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Surrogate Antigen Processing Mediated by TAP-dependent Antigenic Peptide Secretion
MHC class I proteins assemble with peptides in the ER. The peptides are predominantly generated from cytoplasmic proteins, probably by the action of the proteasome, a multicatalytic proteinase complex. Peptides are translocated into the ER by the transporters associated with antigen processing (TAP)...
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主要な著者: | , , , , , |
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フォーマット: | Artigo |
言語: | Inglês |
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The Rockefeller University Press
1998
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主題: | |
オンライン・アクセス: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2132598/ https://ncbi.nlm.nih.gov/pubmed/9425150 |
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