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Surrogate Antigen Processing Mediated by TAP-dependent Antigenic Peptide Secretion

MHC class I proteins assemble with peptides in the ER. The peptides are predominantly generated from cytoplasmic proteins, probably by the action of the proteasome, a multicatalytic proteinase complex. Peptides are translocated into the ER by the transporters associated with antigen processing (TAP)...

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Detalhes bibliográficos
Main Authors: Gabathuler, Reinhard, Alimonti, Judie, Zhang, Qian-Jin, Kolaitis, Gerassimos, Reid, Gregor, Jefferies, Wilfred A.
Formato: Artigo
Idioma:Inglês
Publicado em: The Rockefeller University Press 1998
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2132598/
https://ncbi.nlm.nih.gov/pubmed/9425150
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