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Mrg15 null and heterozygous mouse embryonic fibroblasts exhibit DNA repair defects post exposure to gamma ionizing radiation
MRG15 is a core component of the NuA4/Tip60 histone acetyltransferase complex that modifies chromatin structure. We here demonstrate that Mrg15 null and heterozygous mouse embryonic fibroblasts exhibit an impaired DNA damage response post gamma irradiation, when compared to wild-type cells. Defects...
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| Principais autores: | , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2007
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2132445/ https://ncbi.nlm.nih.gov/pubmed/17961556 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.febslet.2007.10.017 |
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