Molecular cloning and characterization of human caspase-activated DNase

Caspase-activated DNase (CAD) cleaves chromosomal DNA during apoptosis. Here, we report isolation of two classes of human CAD cDNAs from a human KT-3 leukemic cell cDNA library. One class of cDNA encoded a protein comprising 338 amino acids, which showed a marked similarity to its murine counterpart...

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Autori principali: Mukae, Naomi, Enari, Masato, Sakahira, Hideki, Fukuda, Yoji, Inazawa, Johji, Toh, Hiroyuki, Nagata, Shigekazu
Natura: Artigo
Lingua:Inglês
Pubblicazione: The National Academy of Sciences 1998
Soggetti:
Biological Sciences
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC21302/
https://ncbi.nlm.nih.gov/pubmed/9689044
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