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The pathogenicity of thymidine kinase-deficient mutants of herpes simplex virus in mice.

The pathogenicity for mice of two mutants of herpes simplex virus (type 1 and type 2), which fail to induce thymidine kinase, were compared with their respective parent strains. The mutants were much less virulent than the parents following either intracerebral or peripheral inoculation. The replica...

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Autors principals: Field, H. J., Wildy, P.
Format: Artigo
Idioma:Inglês
Publicat: Cambridge University Press 1978
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC2129783/
https://ncbi.nlm.nih.gov/pubmed/212476
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