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Anthracycline metabolites of tetracenomycin C-nonproducing Streptomyces glaucescens mutants.

Mutants of Streptomyces glaucescens GLA.0 which are blocked in the production of tetracenomycin C (compound 1), an anthracycline antibiotic having significant antitumor activity, accumulated several new anthracycline metabolites structurally related to compound 1 and to intermediates of its biosynth...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Yue, S, Motamedi, H, Wendt-Pienkowski, E, Hutchinson, C R
Format: Artigo
Sprache:Inglês
Veröffentlicht: 1986
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC212929/
https://ncbi.nlm.nih.gov/pubmed/3460987
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