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Role of leader peptide synthesis in tryptophanase operon expression in Escherichia coli K-12.

We used site-directed mutagenesis to replace the Escherichia coli tryptophanase (tna) operon leader peptide start codon with AUC. This change greatly decreased the uninduced rate of tna operon expression, and it also lowered the response to inducer. We conclude that leader peptide synthesis plays an...

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Detalhes bibliográficos
Main Authors: Stewart, V, Yanofsky, C
Formato: Artigo
Idioma:Inglês
Publicado em: 1986
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC212888/
https://ncbi.nlm.nih.gov/pubmed/3522554
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