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The uncompetitive N-methyl-D-aspartate (NMDA) receptor antagonist memantine prolongs spatial memory in a rat delayed radial arm maze memory task

In the present study, we evaluated the effects of memantine in a delayed radial arm maze rat task, consisting of an acquisition phase followed 18 h later by a win-shift retrieval test. When administered 20 min before acquisition, memantine elicited an inverted U-shape dose-response relationship, wit...

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Detalhes bibliográficos
Main Authors: Wise, Laura E., Lichtman, Aron H.
Formato: Artigo
Idioma:Inglês
Publicado em: 2007
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2128866/
https://ncbi.nlm.nih.gov/pubmed/17850786
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ejphar.2007.07.059
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