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Protection from Experimental Asthma by an Endogenous Bronchodilator

Mechanisms that protect against asthma remain poorly understood. S-nitrosoglutathione (GSNO), an endogenous bronchodilator, is depleted from asthmatic airways, suggesting a protective role. We report that, following allergen challenge, wild-type mice exhibiting airway hyperresponsivity have increase...

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Hlavní autoři: Que, Loretta G., Liu, Limin, Yan, Yun, Whitehead, Gregory S., Gavett, Stephen H., Schwartz, David A., Stamler, Jonathan S.
Médium: Artigo
Jazyk:Inglês
Vydáno: 2005
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC2128762/
https://ncbi.nlm.nih.gov/pubmed/15919956
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1126/science.1108228
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