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Rad54 oligomers translocate and cross-bridge double-stranded DNA to stimulate synapsis

Rad54 is a key component of the eukaryotic recombination machinery. Its presence in DNA strand exchange reactions in vitro results in a significant stimulation in the overall reaction rate. Using untagged Rad54, we show that this stimulation can be attributed to enhancement of the formation of a key...

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Hlavní autoři: Bianco, Piero R., Bradfield, Justin J., Castanza, Lauren R., Donnelly, Andrea N.
Médium: Artigo
Jazyk:Inglês
Vydáno: 2007
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC2128729/
https://ncbi.nlm.nih.gov/pubmed/17949748
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jmb.2007.09.052
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