Intradermal Administration of DNA Vaccines Combining a Strategy to Bypass Antigen Processing with a Strategy to Prolong Dendritic Cell Survival Enhances DNA Vaccine Potency

Intradermal vaccination via gene gun efficiently delivers DNA vaccines into dendritic cells (DCs) of the skin, resulting in the activation and priming of antigen-specific T cells in vivo. We have previously demonstrated that intradermal delivery of DNA vaccines encoding single-chain trimer (SCT) com...

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Autores principales: Huang, Bruce, Mao, Chih-Ping, Peng, Shiwen, He, Liangmei, Hung, Chien-Fu, Wu, T.-C.
Formato: Artigo
Lenguaje:Inglês
Publicado: 2007
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Article
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC2128728/
https://ncbi.nlm.nih.gov/pubmed/17931752
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.vaccine.2007.08.036
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