Intradermal Administration of DNA Vaccines Combining a Strategy to Bypass Antigen Processing with a Strategy to Prolong Dendritic Cell Survival Enhances DNA Vaccine Potency

Intradermal vaccination via gene gun efficiently delivers DNA vaccines into dendritic cells (DCs) of the skin, resulting in the activation and priming of antigen-specific T cells in vivo. We have previously demonstrated that intradermal delivery of DNA vaccines encoding single-chain trimer (SCT) com...

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Bibliographic Details
Main Authors: Huang, Bruce, Mao, Chih-Ping, Peng, Shiwen, He, Liangmei, Hung, Chien-Fu, Wu, T.-C.
Format: Artigo
Language:Inglês
Published: 2007
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Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC2128728/
https://ncbi.nlm.nih.gov/pubmed/17931752
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.vaccine.2007.08.036
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