Intradermal Administration of DNA Vaccines Combining a Strategy to Bypass Antigen Processing with a Strategy to Prolong Dendritic Cell Survival Enhances DNA Vaccine Potency

Intradermal vaccination via gene gun efficiently delivers DNA vaccines into dendritic cells (DCs) of the skin, resulting in the activation and priming of antigen-specific T cells in vivo. We have previously demonstrated that intradermal delivery of DNA vaccines encoding single-chain trimer (SCT) com...

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Bibliographische Detailangaben
Hauptverfasser: Huang, Bruce, Mao, Chih-Ping, Peng, Shiwen, He, Liangmei, Hung, Chien-Fu, Wu, T.-C.
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2007
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Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2128728/
https://ncbi.nlm.nih.gov/pubmed/17931752
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.vaccine.2007.08.036
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