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Granule Cell Dispersion and Aberrant Neurogenesis in the Adult Hippocampus of an LIS1 Mutant Mouse

Human type 1 lissencephaly is a severe brain malformation associated with cognitive dysfunction and intractable epilepsy. Mutant mice with a heterozygous deletion of LIS1 show varying degrees of hippocampal abnormality and enhanced excitability. Whether a reduction of LIS1 function affects adult hip...

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Bibliografski detalji
Glavni autori: Wang, Yanling, Baraban, Scott C.
Format: Artigo
Jezik:Inglês
Izdano: 2007
Teme:
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC2128724/
https://ncbi.nlm.nih.gov/pubmed/17148952
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1159/000096214
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