Cyclic AMP regulates bicarbonate secretion in cholangiocytes through release of ATP into bile

BACKGROUND & AIMS: Bicarbonate secretion is a primary function of cholangiocytes. Either cAMP or cytosolic Ca(2+) can mediate bicarbonate secretion, but these are thought to act through separate pathways. We examined the role of the inositol 1,4,5-trisphosphate receptor (InsP3R) in mediating bic...

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Main Authors: Minagawa, Noritaka, Nagata, Jun, Shibao, Kazunori, Masyuk, Anatoliy I., Gomes, Dawidson A., Rodrigues, Michele A., LeSage, Gene, Akiba, Yasutada, Kaunitz, Jonathan D., Ehrlich, Barbara E., LaRusso, Nicholas F., Nathanson, Michael H.
Formato: Artigo
Idioma:Inglês
Publicado: 2007
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Article
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC2128713/
https://ncbi.nlm.nih.gov/pubmed/17916355
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1053/j.gastro.2007.08.020
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