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Determination of DNA minor groove width in distamycin-DNA complexes by solid-state NMR

We have performed solid-state (31)P-(19)F REDOR nuclear magnetic resonance (NMR) experiments to monitor changes in minor groove width of the oligonucleotide d(CGCAAA(2′F)UTGGC)·d(GCCAAT(pS)TT GCG) (A(3)T(2)) upon binding of the drug distamycin A at different stoichiometries. In the hydrated solid-st...

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Bibliographic Details
Published in:Nucleic Acids Res
Main Authors: Olsen, Greg L., Louie, Elizabeth A., Drobny, Gary P., Sigurdsson, Snorri Th.
Format: Artigo
Language:Inglês
Published: Oxford University Press 2003
Subjects:
Online Access:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC212816/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/12930959/
https://ncbi.nlm.nih.govhttps://doi.org/10.1093/nar/gkg720
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