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Complex Systems Biology Approach To Understanding Coordination of JAK-STAT Signaling
In this work, we search for coordination as an organizing principle in a complex signaling system using a multilevel hierarchical paradigm. The objective is to explain the underlying mechanism of Interferon (IFN(γ)) induced JAK-STAT (specifically JAK1/JAK2-STAT1) pathway behavior. Starting with a ma...
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| Main Authors: | , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2007
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2128044/ https://ncbi.nlm.nih.gov/pubmed/17646048 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.biosystems.2007.05.005 |
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