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Crystal structure of the human RXRα ligand-binding domain bound to its natural ligand: 9-cis retinoic acid
The pleiotropic effects of active retinoids are transduced by their cognate nuclear receptors, retinoid X receptors (RXRs) and retinoic acid receptors (RARs), which act as transcriptional regulators activated by two stereoisomers of retinoic acid (RA): 9-cis RA (9-cRA) and all-trans RA (a-tRA). Amon...
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| Autori principali: | , , , , , |
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| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
Oxford University Press
2000
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| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC212755/ https://ncbi.nlm.nih.gov/pubmed/10835357 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/emboj/19.11.2592 |
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