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Crystal structure of the human RXRα ligand-binding domain bound to its natural ligand: 9-cis retinoic acid

The pleiotropic effects of active retinoids are transduced by their cognate nuclear receptors, retinoid X receptors (RXRs) and retinoic acid receptors (RARs), which act as transcriptional regulators activated by two stereoisomers of retinoic acid (RA): 9-cis RA (9-cRA) and all-trans RA (a-tRA). Amon...

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Dades bibliogràfiques
Publicat a:EMBO J
Autors principals: Egea, Pascal F., Mitschler, André, Rochel, Natacha, Ruff, Marc, Chambon, Pierre, Moras, Dino
Format: Artigo
Idioma:Inglês
Publicat: Nature Publishing Group 2000
Matèries:
Accés en línia:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC212755/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/10835357/
https://ncbi.nlm.nih.govhttps://doi.org/10.1093/emboj/19.11.2592
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