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Locus specificity determinants in the multifunctional yeast silencing protein Sir2

Yeast SIR2, the founding member of a conserved gene family, acts to modulate chromatin structure in three different contexts: silent (HM) mating-type loci, telomeres and rDNA. At HM loci and telomeres, Sir2p forms a complex with Sir3p and Sir4p. However, Sir2p’s role in rDNA silencing is Sir3/4 inde...

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Autori principali: Cuperus, Guido, Shafaatian, Reza, Shore, David
Natura: Artigo
Lingua:Inglês
Pubblicazione: Oxford University Press 2000
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC212746/
https://ncbi.nlm.nih.gov/pubmed/10835361
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/emboj/19.11.2641
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