Substitution of active-site His-223 in Pseudomonas aeruginosa elastase and expression of the mutated lasB alleles in Escherichia coli show evidence for autoproteolytic processing of proelastase.

Lignende værker

• Pseudomonas aeruginosa lasB1 mutants produce an elastase, substituted at active-site His-223, that is defective in activity, processing, and secretion.
  af: McIver, K S, et al.
  Udgivet: (1993)
• Analysis of the Pseudomonas aeruginosa elastase (lasB) regulatory region.
  af: Rust, L, et al.
  Udgivet: (1996)
• A Second Operator Is Involved in Pseudomonas aeruginosa Elastase (lasB) Activation
  af: Anderson, Ronda M., et al.
  Udgivet: (1999)
• Site-directed mutagenesis of Glu-141 and His-223 in Pseudomonas aeruginosa elastase: catalytic activity, processing, and protective activity of the elastase against Pseudomonas infection.
  af: Kawamoto, S, et al.
  Udgivet: (1993)
• A substitution at His-120 in the LasA protease of Pseudomonas aeruginosa blocks enzymatic activity without affecting propeptide processing or extracellular secretion.
  af: Gustin, J K, et al.
  Udgivet: (1996)