Site and substrate specificity of the ermC 23S rRNA methyltransferase.

The purified ermC methyltransferase described here incorporates two methyl groups per Bacillus subtilis 23S rRNA molecule in vitro. The Km for S-adenosyl-L-methionine was 12 microM, and for B. subtilis 23S rRNA the Km was 375 nM. In vivo methylation specified by several related resistance determinan...

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Veröffentlicht in:	J Bacteriol
Hauptverfasser:	Denoya, C D, Dubnau, D
Format:	Artigo
Sprache:	Inglês
Veröffentlicht:	American Society for Microbiology (ASM) 1987
Schlagworte:	Research Article
Online-Zugang:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC212483/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/2440853/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/jb.169.8.3857-3860.1987
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