The Guanine Nucleotide Exchange Factor ARNO mediates the activation of ARF and phospholipase D by insulin

BACKGROUND: Phospholipase D (PLD) is involved in many signaling pathways. In most systems, the activity of PLD is primarily regulated by the members of the ADP-Ribosylation Factor (ARF) family of GTPases, but the mechanism of activation of PLD and ARF by extracellular signals has not been fully esta...

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Hauptverfasser: Li, Hai-Sheng, Shome, Kuntala, Rojas, Raúl, Rizzo, Megan A, Vasudevan, Chandrasekaran, Fluharty, Eric, Santy, Lorraine C, Casanova, James E, Romero, Guillermo
Format: Artigo
Sprache:Inglês
Veröffentlicht: BioMed Central 2003
Schlagworte:
Research Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC212319/
https://ncbi.nlm.nih.gov/pubmed/12969509
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1471-2121-4-13
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