Mice with targeted disruption of p8 gene show increased sensitivity to lipopolysaccharide and DNA microarray analysis of livers reveals an aberrant gene expression response

BACKGROUND: p8 is a DNA-binding protein induced in many tissues in response to LPS treatment. Hence, p8 could be a mediator of LPS-associated effects or, on the contrary, p8 expression may be part of the protective mechanism of the tissues in response to LPS. Finally, p8 expression in response to LP...

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Detalhes bibliográficos
Main Authors: Vasseur, Sophie, Hoffmeister, Albrecht, Garcia-Montero, Andrés, Barthet, Marc, Saint-Michel, Laure, Berthézène, Patrice, Fiedler, Fritz, Closa, Daniel, Dagorn, Jean Charles, Iovanna, Juan Lucio
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2003
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC212298/
https://ncbi.nlm.nih.gov/pubmed/12959645
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1471-230X-3-25
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