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Molecular genetic studies of a human epidermal autoantigen (the 180-kD bullous pemphigoid antigen/BP180): identification of functionally important sequences within the BP180 molecule and evidence for an interaction between BP180 and alpha 6 integrin

The 180-kD bullous pemphigoid autoantigen (BP180) is a component of the hemidesmosome, a cell-matrix connector. This protein is oriented in a type II fashion in the membrane of the hemidesmosome and is a hybrid collagen (classified as type XVII). We have analyzed the fate of various mutant BP180 mol...

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Detalles Bibliográficos
Formato: Artigo
Lenguaje:Inglês
Publicado: The Rockefeller University Press 1995
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Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC2120509/
https://ncbi.nlm.nih.gov/pubmed/7790367
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