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The carboxy termini of Sir4 and Rap1 affect Sir3 localization: evidence for a multicomponent complex required for yeast telomeric silencing

The Silent Information Regulatory proteins, Sir3 and Sir4, and the telomeric repeat-binding protein RAP1 are required for the chromatin- mediated gene repression observed at yeast telomeric regions. All three proteins are localized by immunofluorescence staining to foci near the nuclear periphery su...

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Format: Artigo
Idioma:Inglês
Publicat: The Rockefeller University Press 1995
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC2120499/
https://ncbi.nlm.nih.gov/pubmed/7744964
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