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Inactivation of the ampD gene causes semiconstitutive overproduction of the inducible Citrobacter freundii beta-lactamase.

In Citrobacter freundii and Enterobacter cloacae, synthesis of AmpC beta-lactamase is inducible by the addition of beta-lactams to the growth medium. Spontaneous mutants that constitutively overproduce the enzyme occur at a high frequency. When the C. freundii ampC beta-lactamase gene is cloned into...

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Detaylı Bibliyografya
Yayımlandı:J Bacteriol
Asıl Yazarlar: Lindberg, F, Lindquist, S, Normark, S
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: American Society for Microbiology (ASM) 1987
Konular:
Online Erişim:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC212046/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/3032901/
https://ncbi.nlm.nih.govhttps://doi.org/10.1128/jb.169.5.1923-1928.1987
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