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Activation of the alpha 4 beta 1 integrin through the beta 1 subunit induces recognition of the RGDS sequence in fibronectin

Lymphocyte attachment to fibronectin is mainly mediated by the interaction of alpha 5 beta 1 and alpha 4 beta 1 integrins with the RGD and CS-1/Hep II sites, respectively. We have recently shown that the anti-beta 1 mAb TS2/16 can convert the partly active alpha 4 beta 1 present on certain hemopoiet...

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Format: Artigo
Idioma:Inglês
Publicat: The Rockefeller University Press 1994
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC2120104/
https://ncbi.nlm.nih.gov/pubmed/7517944
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