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Induction of cell migration by pro-urokinase binding to its receptor: possible mechanism for signal transduction in human epithelial cells

A human epithelial cell line, WISH, and a mouse cell line, LB6-uPAR, transfected with the human urokinase receptor (uPAR), both expressed high affinity uPAR but undetectable levels of urokinase (uPA). In two independent assays, binding of exogenous pro-uPA produced an up to threefold enhancement of...

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Format: Artigo
Idioma:Inglês
Publicat: The Rockefeller University Press 1994
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC2120093/
https://ncbi.nlm.nih.gov/pubmed/7517943
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