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A hyaluronidase activity of the sperm plasma membrane protein PH-20 enables sperm to penetrate the cumulus cell layer surrounding the egg

A typical mammalian egg is surrounded by an outer layer of about 3,000 cumulus cells embedded in an extracellular matrix rich in hyaluronic acid. A current, widely proposed model is that the fertilizing sperm, while it is acrosome intact, passes through the cumulus cell layer and binds to the egg zo...

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Bibliografiset tiedot
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: The Rockefeller University Press 1994
Aiheet:
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC2120058/
https://ncbi.nlm.nih.gov/pubmed/8195297
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