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A GDP-bound of rab1 inhibits protein export from the endoplasmic reticulum and transport between Golgi compartments
Rab1 is a small GTPase regulating vesicular traffic between early compartments of the secretory pathway. To explore the role of rab1 we have analyzed the function of a mutant (rab1a[S25N]) containing a substitution which perturbs Mg2+ coordination and reduces the affinity for GTP, resulting in a for...
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| Formato: | Artigo |
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| Lenguaje: | Inglês |
| Publicado: |
The Rockefeller University Press
1994
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| Materias: | |
| Acceso en línea: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2120023/ https://ncbi.nlm.nih.gov/pubmed/8163542 |
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