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Depletion of 43-kD growth-associated protein in primary sensory neurons leads to diminished formation and spreading of growth cones

The 43-kD growth-associated protein (GAP-43) is a major protein kinase C (PKC) substrate of growing axons, and of developing nerve terminals and glial cells. It is a highly hydrophilic protein associated with the cortical cytoskeleton and membranes. In neurons it is rapidly transported from the cell...

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Format: Artigo
Langue:Inglês
Publié: The Rockefeller University Press 1993
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Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC2119839/
https://ncbi.nlm.nih.gov/pubmed/8408223
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