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Mannose 6-phosphate-independent targeting of lysosomal enzymes in I- cell disease B lymphoblasts

B lymphocytes from patients with I-cell disease (ICD) maintain normal cellular levels of lysosomal enzymes despite a deficiency of the enzyme UDP-N-acetylglucosamine: lysosomal enzyme N-acetylglucosamine-1- phosphotransferase. We find that an ICD B lymphoblastoid cell line targets about 45% of the l...

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Bibliografische gegevens
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: The Rockefeller University Press 1993
Onderwerpen:
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2119824/
https://ncbi.nlm.nih.gov/pubmed/8408210
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