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Preventing re-replication of DNA in a single cell cycle: evidence for a replication licensing factor

Xenopus egg extracts treated with the protein kinase inhibitor 6- dimethylaminopurine (6-DMAP) are unable to support the initiation of DNA replication. Nuclei assembled in 6-DMAP extracts behave as though they are in G2, and will not undergo another round of DNA replication until passage through mit...

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Detalhes bibliográficos
Formato: Artigo
Idioma:Inglês
Publicado em: The Rockefeller University Press 1993
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2119628/
https://ncbi.nlm.nih.gov/pubmed/8354699
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