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Protein kinase C-dependent effects of 12(S)-HETE on endothelial cell vitronectin receptor and fibronectin receptor

12(S)-HETE, a lipoxygenase metabolite of arachidonic acid induced a nondestructive and reversible endothelial cell (EC) retraction. 12(S)- HETE induced EC retraction was inhibited by protein kinase C inhibitors calphostin C and staurosporine but not by the protein kinase A inhibitor H8. The role of...

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Formato: Artigo
Lenguaje:Inglês
Publicado: The Rockefeller University Press 1993
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Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC2119558/
https://ncbi.nlm.nih.gov/pubmed/7683691
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