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CD4 expression is differentially required for deletion of MLS-1a- reactive T cells

Clonal deletion of thymocytes expressing potentially self-reactive T cell receptors (TCRs) occurs during thymocyte ontogeny. Mice deficient for CD4 expression provide a unique model system to study the contribution of the CD4 molecule in negative selection of T cells reactive against the major histo...

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Detalles Bibliográficos
Formato: Artigo
Idioma:Inglês
Publicado: The Rockefeller University Press 1992
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC2119409/
https://ncbi.nlm.nih.gov/pubmed/1402689
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