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Immunoglobulin (Ig) mu, kappa transgenic mice express transgenic idiotype on endogenously rearranged IgM and IgA molecules by secretion of chimeric molecules

The sera of C57BL/6 mice transgenic for a mu a allotype heavy (H) chain and kappa light chain gene contained endogenous nontransgene immunoglobulin (IgM) (mu b allotype) and IgA molecules which carried the idiotype expressed by the transgenically encoded IgM (mu a) molecule. Serological analysis dem...

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Natura: Artigo
Lingua:Inglês
Pubblicazione: The Rockefeller University Press 1992
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC2119396/
https://ncbi.nlm.nih.gov/pubmed/1402667
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