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Tn5 insertion in the polynucleotide phosphorylase (pnp) gene in Escherichia coli increases susceptibility to antibiotics.

A Tn5 insertional mutation on the Escherichia coli chromosome which caused a severalfold increase in susceptibility to structurally and functionally diverse antibiotics was found to map within the gene for polynucleotide phosphorylase (pnp) and to inactivate this enzyme, which is involved in RNA bre...

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Udgivet i:J Bacteriol
Principais autores: McMurry, L M, Levy, S B
Format: Artigo
Sprog:Inglês
Udgivet: American Society for Microbiology (ASM) 1987
Fag:
Research Article
Online adgang:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC211937/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/3029034/
https://ncbi.nlm.nih.govhttps://doi.org/10.1128/jb.169.3.1321-1324.1987
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