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A polyalanine peptide with only five native myelin basic protein residues induces autoimmune encephalomyelitis
The minimum structural requirements for peptide interactions with major histocompatibility complex (MHC) class II molecules and with T cell receptors (TCRs) were examined. In this report we show that substituting alanines at all but five amino acids in the myelin basic protein (MBP) peptide Ac1-11 d...
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| フォーマット: | Artigo |
|---|---|
| 言語: | Inglês |
| 出版事項: |
The Rockefeller University Press
1992
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| 主題: | |
| オンライン･アクセス: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2119337/ https://ncbi.nlm.nih.gov/pubmed/1380066 |
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