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Extracellular processing of peptide antigens that bind class I major histocompatibility molecules

One problem associated with the use of synthetic peptides as antigens in vivo is their susceptibility to inactivation by proteolytic degradation. A situation is described in which a serum protease, angiotensin-converting enzyme (ACE), is actually responsible for the class I binding activity of a com...

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Natura: Artigo
Lingua:Inglês
Pubblicazione: The Rockefeller University Press 1992
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC2119214/
https://ncbi.nlm.nih.gov/pubmed/1314884
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