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Tumor suppression after tumor cell-targeted tumor necrosis factor alpha gene transfer
The tumor necrosis factor alpha (TNF-alpha) gene was introduced by retroviral gene transfer into the TNF-alpha-insensitive tumor cell line J558L. Production of 40 pg/ml TNF-alpha by clone J2T12 consistently did not change the growth rate in vitro, but drastically suppressed tumor growth when injecte...
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| Format: | Artigo |
|---|---|
| Sprache: | Inglês |
| Veröffentlicht: |
The Rockefeller University Press
1991
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2118861/ https://ncbi.nlm.nih.gov/pubmed/2022919 |
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