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The immunodeficient scid mouse as a model for human lymphatic filariasis
The C.B.-17-scid/scid mouse (hereafter referred to as the scid mouse) is homozygous for a recessive mutation at a locus that influences the assembly of intact immunoglobulin and T cell receptor genes. Therefore, scid mice cannot generate functional B or T lymphocytes, are profoundly immunodeficient,...
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| Format: | Artigo |
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| Language: | Inglês |
| Published: |
The Rockefeller University Press
1991
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| Subjects: | |
| Online Access: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2118823/ https://ncbi.nlm.nih.gov/pubmed/1997651 |
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