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The V beta repertoire of mouse gut homodimeric alpha CD8+ intraepithelial T cell receptor alpha/beta + lymphocytes reveals a major extrathymic pathway of T cell differentiation

Gut intraepithelial lymphocytes (IEL) contain two independent T cell receptor alpha/beta + T cell populations, with different V beta repertoires. In DBA/2 mice (Mlsa, IE+), the CD4+ and heterodimeric alpha/beta CD8+ thymodependent T cell pool shows the same deletion of V beta 6, 8.1, and 11+ cells a...

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Format: Artigo
Idioma:Inglês
Publicat: The Rockefeller University Press 1991
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC2118783/
https://ncbi.nlm.nih.gov/pubmed/1824858
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