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Role for DNA repair factor XRCC4 in immunoglobulin class switch recombination

V(D)J recombination and immunoglobulin class switch recombination (CSR) are two somatic rearrangement mechanisms that proceed through the introduction of double-strand breaks (DSBs) in DNA. Although the DNA repair factor XRCC4 is essential for the resolution of DNA DSB during V(D)J recombination, it...

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Main Authors: Soulas-Sprauel, Pauline, Le Guyader, Gwenaël, Rivera-Munoz, Paola, Abramowski, Vincent, Olivier-Martin, Christelle, Goujet-Zalc, Cécile, Charneau, Pierre, de Villartay, Jean-Pierre
Formato: Artigo
Idioma:Inglês
Publicado: The Rockefeller University Press 2007
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC2118634/
https://ncbi.nlm.nih.gov/pubmed/17606631
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1084/jem.20070255
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