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Distinct vascular endothelial growth factor signals for lymphatic vessel enlargement and sprouting

Lymphatic vessel growth, or lymphangiogenesis, is regulated by vascular endothelial growth factor-C (VEGF-C) and -D via VEGF receptor 3 (VEGFR-3). Recent studies suggest that VEGF, which does not bind to VEGFR-3, can also induce lymphangiogenesis through unknown mechanisms. To dissect the receptor p...

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Détails bibliographiques
Auteurs principaux: Wirzenius, Maria, Tammela, Tuomas, Uutela, Marko, He, Yulong, Odorisio, Teresa, Zambruno, Giovanna, Nagy, Janice A., Dvorak, Harold F., Ylä-Herttuala, Seppo, Shibuya, Masabumi, Alitalo, Kari
Format: Artigo
Langue:Inglês
Publié: The Rockefeller University Press 2007
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC2118625/
https://ncbi.nlm.nih.gov/pubmed/17535974
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1084/jem.20062642
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