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Selective blockade of the inhibitory Fcγ receptor (FcγRIIB) in human dendritic cells and monocytes induces a type I interferon response program

The ability of dendritic cells (DCs) to activate immunity is linked to their maturation status. In prior studies, we have shown that selective antibody-mediated blockade of inhibitory FcγRIIB receptor on human DCs in the presence of activating immunoglobulin (Ig) ligands leads to DC maturation and e...

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Detalhes bibliográficos
Main Authors: Dhodapkar, Kavita M., Banerjee, Devi, Connolly, John, Kukreja, Anjli, Matayeva, Elyana, Veri, Maria Concetta, Ravetch, Jeffrey V., Steinman, Ralph M., Dhodapkar, Madhav V.
Formato: Artigo
Idioma:Inglês
Publicado em: The Rockefeller University Press 2007
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2118610/
https://ncbi.nlm.nih.gov/pubmed/17502666
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1084/jem.20062545
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