Lysosomal integral membrane protein 2 is a novel component of the cardiac intercalated disc and vital for load-induced cardiac myocyte hypertrophy

The intercalated disc (ID) of cardiac myocytes is emerging as a crucial structure in the heart. Loss of ID proteins like N-cadherin causes lethal cardiac abnormalities, and mutations in ID proteins cause human cardiomyopathy. A comprehensive screen for novel mechanisms in failing hearts demonstrated...

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Main Authors: Schroen, Blanche, Leenders, Joost J., van Erk, Arie, Bertrand, Anne T., van Loon, Mirjam, van Leeuwen, Rick E., Kubben, Nard, Duisters, Rudy F., Schellings, Mark W., Janssen, Ben J., Debets, Jacques J., Schwake, Michael, Høydal, Morten A., Heymans, Stephane, Saftig, Paul, Pinto, Yigal M.
Format: Artigo
Jezik:Inglês
Izdano: The Rockefeller University Press 2007
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Articles
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC2118572/
https://ncbi.nlm.nih.gov/pubmed/17485520
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1084/jem.20070145
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