The humoral pattern recognition receptor PTX3 is stored in neutrophil granules and localizes in extracellular traps

The long pentraxin (PTX) 3 is produced by macrophages and myeloid dendritic cells in response to Toll-like receptor agonists and represents a nonredundant component of humoral innate immunity against selected pathogens. We report that, unexpectedly, PTX3 is stored in specific granules and undergoes...

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Autori principali: Jaillon, Sébastien, Peri, Giuseppe, Delneste, Yves, Frémaux, Isabelle, Doni, Andrea, Moalli, Federica, Garlanda, Cecilia, Romani, Luigina, Gascan, Hugues, Bellocchio, Silvia, Bozza, Silvia, Cassatella, Marco A., Jeannin, Pascale, Mantovani, Alberto
Natura: Artigo
Lingua:Inglês
Pubblicazione: The Rockefeller University Press 2007
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC2118544/
https://ncbi.nlm.nih.gov/pubmed/17389238
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1084/jem.20061301
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