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Class A scavenger receptors regulate tolerance against apoptotic cells, and autoantibodies against these receptors are predictive of systemic lupus

Apoptotic cells are considered to be a major source for autoantigens in autoimmune diseases such as systemic lupus erythematosus (SLE). In agreement with this, defective clearance of apoptotic cells has been shown to increase disease susceptibility. Still, little is known about how apoptotic cell–de...

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Hlavní autoři: Wermeling, Fredrik, Chen, Yunying, Pikkarainen, Timo, Scheynius, Annika, Winqvist, Ola, Izui, Shozo, Ravetch, Jeffrey V., Tryggvason, Karl, Karlsson, Mikael C.I.
Médium: Artigo
Jazyk:Inglês
Vydáno: The Rockefeller University Press 2007
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC2118440/
https://ncbi.nlm.nih.gov/pubmed/17893199
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1084/jem.20070600
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