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Selective dysregulation of the FcγIIB receptor on memory B cells in SLE

The inappropriate expansion and activation of autoreactive memory B cells and plasmablasts contributes to loss of self-tolerance in systemic lupus erythematosus (SLE). Defects in the inhibitory Fc receptor, FcγRIIB, have been shown to contribute to B cell activation and autoimmunity in several mouse...

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Autores principales: Mackay, Meggan, Stanevsky, Anfisa, Wang, Tao, Aranow, Cynthia, Li, Margaret, Koenig, Scott, Ravetch, Jeffrey V., Diamond, Betty
Formato: Artigo
Lenguaje:Inglês
Publicado: The Rockefeller University Press 2006
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Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC2118390/
https://ncbi.nlm.nih.gov/pubmed/16923849
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1084/jem.20051503
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